Теоретичні питання взаємодії оперативних підрозділів між собою та з іншими правоохоронними службами при здійсненні особистого пошуку

Солоха, В. Є. Теоретичні питання взаємодії оперативних підрозділів між собою та з іншими правоохоронними службами при здійсненні особистого пошуку / В. Є. Солоха // Вісник Національного університету внутрішніх справ. - 2005. – Вип. 31. - С. 51-54Підкреслено, що питання взаємодії та координації діяльності оперативних підрозділів набувають особливої актуальності, коли злочинність носить різноманітний характер, глибоко законспірована, а їй протистоїть діяльність розгалуженої мережі підрозділів правоохоронних органів. Все це потребує упорядкування, взаємозв’язку, узгодженості їх спільних дій, відповідної підпорядкованості і маневру силами та засобами. Подчеркнуто, что вопросы взаимодействия и координации деятельности оперативных подразделений приобретают особую актуальность, когда преступность носит разнообразный характер, глубоко законспирированная, а ей противостоит деятельность разветвленной сети подразделений правоохранительных органов. Все это требует упорядочения, взаимосвязи, согласованности их совместных действий, соответствующей подчиненности и маневра силами и средствами. It is emphasized that the issues of interaction and coordination of the activities of operational units acquire special relevance when crime is diverse, deeply conspiracy, and it is opposed by an extensive network of law enforcement units. All this requires streamlining, interconnection, coordination of their joint actions, appropriate subordination and maneuver by forces and means

DIAGNOSTIC VALUE OF THE DEJA VU PHENOMENON IN THE CLINICAL PICTURE OF GLIAL BRAIN TUMORS

In growing glial tumors, epileptic seizures are the first and only symptom of the disease in more than a third of cases. The seizure is commonly characterized by only psychopathological disorders that are frequently ignored by both patients and physicians. The deja vu (DV) phenomenon may be one of such symptoms. Its specific feature is that it occurs in both healthy individuals and patients with various brain pathologies. This investigation was undertaken to study the implication of the DV phenomenon in the clinical picture of glial brain tumors (GBT). One hundred and sixty-one subjects (mean age 29,2±6,4 years; males 47%), including 129 healthy individuals and 32 patients with GBT, were examined. In the clinical picture of GBT with seizures, DV is a common symptom that is encountered in the involvement of predominantly the right temporal lobe and accompanied by generalized convulsive attacks and olfactory hallucinations. DV in GBT occurs more than once daily; its duration is a few (as many as 5) minutes; DV is characterized by a negative emotional tinge and attended by fear

Experimental distinction of the molecularly induced Balmer emission contribution and its application for inferring molecular divertor density with 2D filtered camera measurements during detachment in JET L-mode plasmas

A previously presented model for generating 2D estimates of the divertor plasma conditions at JET from deuterium Balmer line intensity ratios, obtained from tomographic reconstructions of divertor camera images, was amended to consider also the Balmer emission arising from molecular processes. Utilizing the AMJUEL and H2VIBR atomic and molecular databases of EIRENE enabled also inference of the molecular divertor density from the distinguished molecularly induced emission. Analysis of a JET L-mode density scan suggests the molecularly induced emission accounting for up to 60%-70% and 10%-20% of the Balmer D-alpha and D-gamma intensities, respectively, at the onset of detachment, while electron-ion recombination becomes increasingly dominant with deepening detachment. Similar observations were made by post-processing EDGE2D-EIRENE simulations, which indicated significant roles of molecular D-2(+) ions and vibrational excitation of the D-2 molecules as precursors for the molecularly induced emission. The experimentally inferred molecular density at the outer strike point was found to increase monotonously with decreasing strike point temperature, reaching approximately 30%-50% of the local electron density at n(mol,osp) = 1-2 x10(20) m(-3) at T-e,T-osp approximate to 0.7 eV. A further steep increase by a factor of 3-5 was observed with decrease of T-e,T-osp to 0.5 eV. The observations are in qualitative and reasonable quantitative agreement with EDGE2D-EIRENE predictions of n(mol,osp) within the uncertainties of the experimental data.Peer reviewe

Tuberculosis in HIV-infected children in Europe, Thailand and Brazil: paediatric TB-HIV EuroCoord study

SETTING: Centres participating in the Paediatric European Network for Treatment of AIDS (PENTA), including Thailand and Brazil. OBJECTIVE: To describe the incidence, presentation, treatment and treatment outcomes of tuberculosis (TB) in human immunodeficiency virus (HIV) infected children. DESIGN: Observational study of TB diagnosed in HIV-infected children in 2011–2013. RESULTS: Of 4265 children aged <16 years, 127 (3%) were diagnosed with TB: 6 (5%) in Western Europe, 80 (63%) in Eastern Europe, 27 (21%) in Thailand and 14 (11%) in Brazil, with estimated TB incidence rates of respectively 239, 982, 1633 and 2551 per 100 000 person-years (py). The majority (94%) had acquired HIV perinatally. The median age at TB diagnosis was 6.8 years (interquartile range 3.0–11.5). Over half (52%) had advanced/severe World Health Organization stage immunodeficiency; 67 (53%) were not on antiretroviral therapy (ART) at TB diagnosis. Preventive anti-tuberculosis treatment was given to 23% (n = 23) of 102 children diagnosed with HIV before TB. Eleven children had unfavourable TB outcomes: 4 died, 5 did not complete treatment, 1 had recurrent TB and 1 had an unknown outcome. In univariable analysis, previous diagnosis of acquired immune-deficiency syndrome, not being virologically suppressed on ART at TB diagnosis and region (Brazil) were significantly associated with unfavourable TB outcomes. CONCLUSION: Most TB cases were from countries with high TB prevalence. The majority (91%) had favourable outcomes. Universal ART and TB prophylaxis may reduce missed opportunities for TB prevention

Современные методы профилактики ототоксичности аминогликозидов у больных туберкулезом легких

Contemporary publications on possible pharmaceutical treatment of ototoxic effect of aminoglycosides have been analyzed. In this respect, substances with the antioxidant effect seem to be the most promising. Their use in therapeutic doses is not accompanied by adverse reactions, and they do not interfere with the antibacterial effect of anti-tuberculosis drugs. Currently, the mechanisms of the otoprotective action of various antioxidants are being studied.Проведен анализ современной литературы о возможности медикаментозной коррекции ототоксических эффектов аминогликозидов. Наиболее перспективными в данном аспекте представляются вещества с антиоксидантным действием. Их применение в терапевтических дозах не сопровождается нежелательными побочными эффектами, они не влияют на антибактериальное действие противотуберкулезных препаратов. В настоящее время изучаются механизмы отопротекторного действия различных антиоксидантов

Отопротекторная и антиоксидантная активность цитофлавина у пациентов с туберкулезом легких на фоне приема амикацина

The objective: to study the potential otoprotective and antioxidant activity of cytoflavin in new pulmonary tuberculosis patients receiving aminoglycoside amikacin.Subjects and Methods. A randomized controlled trial was conducted and included 90 patients with new infiltrative pulmonary tuberculosis with decay, of both genders aged from 20 to 50 years old. Clinical, paraclinical and statistical methods were used in the study. Audiometric screening was carried out by Diagnostic Audiometer AD 226. The degree of antioxidant protection was determined by the oxidation reaction of ABTS in blood serum and plasma.Results. The study included 4 groups of tuberculosis patients and 1 group of healthy donors. Dissemination of pulmonary tuberculosis in 4 groups was approximately the same and was measured by scores. Prior to the start of treatment in all 4 groups (the group receiving standard chemotherapy (CTX) without amikacin, the group receiving «CTX+amikacin», the group receiving «CTX+cytofl avin», the group receiving «CTX+amikacin+cytofl avin») there was a decrease in blood antioxidant activity compared to Control Group. After 3 months of tuberculosis treatment in all 4 groups, the results improved, while in «CTX+Cytofl avin» Group they were similar to Control Group, and «CTX+Amikacin+Cytofl avin Group», they were only 4.8% less. The elevated level of leukocytes decreased by 10.6% in CTX Group, 16.9% in «CTX+Amikacin» Group, 38.3% in «CTX+Cytofl avin» Group, and 72.3% in «CTX+Amikacin+Cytofl avin» Group. In the study, manifestations of oto- and vestibulotoxicity were found only in the «CTX+Amikacin» Group (in 4/20 (5%)). There were no such cases in «Amikacin+Cytofl avin» Group consisting of 23 patients.Цель исследования: изучение возможной отопротекторной и антиоксидантной активности цитофлавина у пациентов с впервые выявленным туберкулезом легких на фоне приема аминогликозида амикацина.Материалы и методы. Проведено рандомизированное контролируемое исследование с включением 90 больных с впервые выявленным инфильтративным туберкулезом легких с распадом, обоего пола в возрасте от 20 до 50 лет. В исследовании использовались клинические, параклинические и статистические методы. Аудиометрический скрининг осуществлялся на аппарате Diagnostic Audiometer AD 226. Степень антиоксидантной защиты организма определяли по реакции окисления ABTS в сыворотке и плазме крови.Результаты. Для исследования сформированы 4 группы пациентов с туберкулезом и 1 группа – здоровые доноры. Объем распространенности туберкулезного процесса легких в 4 группах был примерно одинаков и измерялся по сумме баллов. До начала лечения во всех 4 группах (группа со стандартной химиотерапией (СХ) без амикацина, группа «СХ+амикацин», группа «СХ+цитофлавин», группа «СХ+амикацин+цитофлавин») имелось снижение антиоксидантной активности крови по сравнению с контролем. После 3 месяцев лечения туберкулеза во всех 4 группах результаты улучшились, но в группе «СХ+цитофлавин» сравнялись с контролем, а в группе «СХ+амикацин+цитофлавин» были меньше всего на 4,8%. Повышенный уровень лейкоцитоза сократился на 10,6% в группе «СХ», на 16,9% – в группе «СХ+амикацин», на 38,3% – в группе «СХ+цитофлавин» и на 72,3% – в группе «СХ+амикацин и цитофлавин». В исследовании проявления ото- и вестибулотоксичности было обнаружено только в группе «СХ+амикацин» (у 4/20 (5%)) пациентов. В группе «амикацин+цитофлавин» из 23 пациентов таких случаев не было.

Spectroscopic camera analysis of the roles of molecularly assisted reaction chains during detachment in JET L-mode plasmas

The roles of the molecularly assisted ionization (MAI), recombination (MAR) and dissociation (MAD) reaction chains with respect to the purely atomic ionization and recombination processes were studied experimentally during detachment in low-confinement mode (L-mode) plasmas in JET with the help of experimentally inferred divertor plasma and neutral conditions, extracted previously from filtered camera observations of deuterium Balmer emission, and the reaction coefficients provided by the ADAS, AMJUEL and H2VIBR atomic and molecular databases. The direct contribution of MAI and MAR in the outer divertor particle balance was found to be inferior to the electron-atom ionization (EAI) and electron-ion recombination (EIR). Near the outer strike point, a strong atom source due to the D+2-driven MAD was, however, observed to correlate with the onset of detachment at outer strike point temperatures of Te,osp = 0.9-2.0 eV via increased plasma-neutral interactions before the increasing dominance of EIR at Te,osp &lt; 0.9 eV, followed by increasing degree of detachment. The analysis was supported by predictions from EDGE2D-EIRENE simulations which were in qualitative agreement with the experimental observations

Shattered pellet injection experiments at JET in support of the ITER disruption mitigation system design

A series of experiments have been executed at JET to assess the efficacy of the newly installed shattered pellet injection (SPI) system in mitigating the effects of disruptions. Issues, important for the ITER disruption mitigation system, such as thermal load mitigation, avoidance of runaway electron (RE) formation, radiation asymmetries during thermal quench mitigation, electromagnetic load control and RE energy dissipation have been addressed over a large parameter range. The efficiency of the mitigation has been examined for the various SPI injection strategies. The paper summarises the results from these JET SPI experiments and discusses their implications for the ITER disruption mitigation scheme

Overview of JET results for optimising ITER operation

The JET 2019–2020 scientific and technological programme exploited the results of years of concerted scientific and engineering work, including the ITER-like wall (ILW: Be wall and W divertor) installed in 2010, improved diagnostic capabilities now fully available, a major neutral beam injection upgrade providing record power in 2019–2020, and tested the technical and procedural preparation for safe operation with tritium. Research along three complementary axes yielded a wealth of new results. Firstly, the JET plasma programme delivered scenarios suitable for high fusion power and alpha particle (α) physics in the coming D–T campaign (DTE2), with record sustained neutron rates, as well as plasmas for clarifying the impact of isotope mass on plasma core, edge and plasma-wall interactions, and for ITER pre-fusion power operation. The efficacy of the newly installed shattered pellet injector for mitigating disruption forces and runaway electrons was demonstrated. Secondly, research on the consequences of long-term exposure to JET-ILW plasma was completed, with emphasis on wall damage and fuel retention, and with analyses of wall materials and dust particles that will help validate assumptions and codes for design and operation of ITER and DEMO. Thirdly, the nuclear technology programme aiming to deliver maximum technological return from operations in D, T and D–T benefited from the highest D–D neutron yield in years, securing results for validating radiation transport and activation codes, and nuclear data for ITER

Overview of JET results for optimising ITER operation

The JET 2019–2020 scientific and technological programme exploited the results of years of concerted scientific and engineering work, including the ITER-like wall (ILW: Be wall and W divertor) installed in 2010, improved diagnostic capabilities now fully available, a major neutral beam injection upgrade providing record power in 2019–2020, and tested the technical and procedural preparation for safe operation with tritium. Research along three complementary axes yielded a wealth of new results. Firstly, the JET plasma programme delivered scenarios suitable for high fusion power and alpha particle (α) physics in the coming D–T campaign (DTE2), with record sustained neutron rates, as well as plasmas for clarifying the impact of isotope mass on plasma core, edge and plasma-wall interactions, and for ITER pre-fusion power operation. The efficacy of the newly installed shattered pellet injector for mitigating disruption forces and runaway electrons was demonstrated. Secondly, research on the consequences of long-term exposure to JET-ILW plasma was completed, with emphasis on wall damage and fuel retention, and with analyses of wall materials and dust particles that will help validate assumptions and codes for design and operation of ITER and DEMO. Thirdly, the nuclear technology programme aiming to deliver maximum technological return from operations in D, T and D–T benefited from the highest D–D neutron yield in years, securing results for validating radiation transport and activation codes, and nuclear data for ITER